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Fermentation technology to produce Teicoplanin


Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. It is a glycopeptide antibiotic extracted from Actinoplanes teichomyceticus, with a similar spectrum of activity to vancomycin. Its mechanism of action is to inhibit bacterial cell wall synthesis. Teicoplanin is marketed by Sanofi-Aventis under the trade name Targocid.

2. Character:

White or yellowish powder

Moisture: 15%



3. Market:

Be in hare demand:1, 000kg/year(global 2005)  

Price:12, 000-17, 000﹩(2006) 

4. Performance Values:

Final titre: 5±0.5 g/l 

Fermentation time: 168±12 hrs

Recovery yield: 55%

5. Contact:

Add:    Room 701B/D, Building B, Science Park Tower, Tsinghua Science Park, Haidian District, Beijing 100084, China
Tel:    +86 10 62795180
Fax:    +86 10 62795182 

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