Fermentation technology to produce Bacitracin Zinc

1. Introduction:

Bacitracin is an antibacterial polypeptide produced by the growth of a gram-positive, spore-forming organism belonging to the licheniformin group of Bacillus subtilis, which acts by interfering with bacterial cell wall synthesis.

Bacitracin zinc is a medicine applied to cuts and other skin wounds to help prevent infection. Bacitracin is a germ-killing medicine called an antibiotic. Small amounts of bacitracin zinc are dissolved in petroleum jelly to create antibiotic ointments.

structural formula

formula：C66H101N17O16SZn 

formula weight：1486.07

CAS：1405-89-6

2. Performance Values

Final titre: 12±1 g/L

Fermentation time: 36-40 hrs

Recovery yield: ≥55%

3. Contact