Fermentation technology to produce Daunorubicin

1.     Presentation of the product

Other names:

for Daunorubicin: Daunomycin, Cerubidin, Rubidomycin

for Doxorubicin: Doxomycin, Adriamycin, Adriacin, Adriablastina

Daunorubicin is an anthracycline antibioticum

Structure

M: C27H29NO10 , Molecular weight 527,53

2. Uses

•Daunorubicin primarily in treatment of acute leukemias.

•Doxorubicin is also used in treatment of various solid tumours including breast, prostatic and testicular carcinomas.

•Therapy includes combination with other chemotherapic agents.

3. Market

Volume

•DOXORUBICIN (ADRIAMYCIN): 450 Kg

•DAUNORUBICIN: 200 Kg

Market prices

•Daunorubicin market price is aprox. 27000.00 USD/Kg

•Doxorubicin market price is 10 USD per 10 mg vial. As bulk it ranges from 95000.00 USD to 125000.00 USD.

4. Production Costs

•Daunomycin direct cost of production is < 1000.00 USD/Kg

•Doxorubicin direct cost of production is < 5000.00 USD/Kg. 

5. Technology

Strain and technological know-how is available

Final titre  3±0.3g/lt

Fermentatiion time 168 hrs

Recovery yield 67 %

6. Contact

Add:    Room 701B/D, Building B, Science Park Tower, Tsinghua Science Park, Haidian District, Beijing 100084, China

Tel:    +86 10 62795180

Fax:    +86 10 62795182 

E-mail:  biotech@ittc.com.cn 

Website: www.coway.com.cn    www.coway-biotech.com