Fermentation Technology to Produce Tacrolimus
1. Production Presentation
TACROLIMUS is a polyene conjugated antibiotic
Crude Formula: C44H69NO12
Molecular Weight: 804,03
2. Strain Classification
TACROLIMUS is produced through fermentation of a special strain of Streptomyces tsukubaensis, modified by chemical (nitroso guanidine) and physical agent (U.V. radiation).
3. Technology
Fermentation titre: 1.5 g/l
Fermentation time: 240±24hrs
Recovery yield: 70 %
4. Contact Us
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Tel: +86 10 62795180
Fax: +86 10 62795182
E-mail: biotech@ittc.com.cn
Website: www.coway.com.cn www.coway-biotech.com