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Fermentation Technology to Produce Tacrolimus

1. Production Presentation

TACROLIMUS is a polyene conjugated antibiotic

Crude Formula: C44H69NO12

Molecular Weight: 804,03

2. Strain Classification

TACROLIMUS is produced through fermentation of a special strain of Streptomyces tsukubaensis, modified by chemical (nitroso guanidine) and physical agent (U.V. radiation).

3. Technology

Fermentation titre: 1.5 g/l

Fermentation time: 240±24hrs

Recovery yield: 70 %

4. Contact Us

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Tel:    +86 10 62795180

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