Fermentation Technology to Produce Penicillin G

1. Product Presentation

Penicillin is a group of antibiotics derived from Penicillium fungi. Penicillin antibiotics are historically significant because they are the first drugs that were effective against many previously serious diseases such as syphilis and Staphylococcus infections. Penicillins are still widely used today, though many types of bacteria are now resistant. All penicillins are Beta-lactam antibiotics and are used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms.

Penicillin core structure. The “R” is the variable group.

Molecular formula: R-C9H11N2O4S

Molecular weight: 334(Penicillin G)

2. Technology

Strain and technological know-how is available from ITTC. 

Final Titer:          >80,000u/ml (lab scale)

                                  90,000-100,000u/ml (industrial scale)

Fermentation time:    220 hrs

Recovery yield:            65%

3. Contact 

Add:    Room 701B/D, Building B, Science Park Tower, Tsinghua Science Park, Haidian District, Beijing 100084, China

Tel:    +86 10 62795180

Fax:    +86 10 62795182 

E-mail:  biotech@ittc.com.cn 

Website: www.coway.com.cn    www.coway-biotech.com