Organic Synthesis

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Chemosynthesis Technology for Rocuronium

1. Product introduction:

Chemical name: 1-[17β-Aloxycety-3α-hydroxy-2β-(morpholin-4-yl)-5α-androstan-16β-yl]-1-(prop-2-enyl)pyrrolidinium bromide

Chemical formula: 

 

CAS: 119302-91-9 

Formula: C32H53BrN2O4 

Formula weight : 609.70

Rocuronium is an aminosteroid non-depolarizing (that is, it does not cause initial stimulation of muscles before weakening them) neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

The market of Rocuronium has been rising rapidly since launched to U.S. in 1994. It is marketed under the trade name of Zemuron in the U.S. and Esmeron in most of other countries.

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