Testosterone

1. Product 

Testosterone (testosteronum): (androsten-4-ol-17b-one-3)

The technology exploited now includes biotechnological 4-androstenedione (AD) production from sitosterol followed by 4 step chemical synthesis of testosterone from AD. The direct biotechnological production of testosterone from sitosterol in a single biotechnological operation is a prosperous alternative for the existing technologies. It is ecologically friendly, economically attractive, based on the use of available materials, allows to economize labour- and energy consumes.

2. Usage

Testosterone is endogenous male sex hormone. In medicinal practice it is applied in an esterified form. Testosterone influences nitrogenous and phosphorous metabolism, expresses anabolic and androgen effect. Testosterone deficiency in the organism results in the derangement of protein anabolism, muscular dystrophy, hyperlipopexia. Testosterone is used in a therapy of different pathological states following by profound protein decay (chronic infectious diseases, emaciation, surgical operations, serious injuries, etc), and under derangement of nitrogenous and phosphorous metabolism. Testosterone medications are prescribed at sexual functional disorders, vascular disorders, for therapy of tumors including cancer tumors.

3. Strain: Non-pathogenic bacterial strain.

4. Substrate: b-Sitosterol (phytosterol).

5. Biotechnology parameters:

1. Substrate concentration (g/l): 5 

2. Duration of microbial transformation stage: 135-145 hrs 

3. Testosterone content in cultivation broth: 48-50% 

4. Yield of crystalline final product - 30-35%

6. Contact

Add:    Room 701B/D, Building B, Science Park Tower, Tsinghua Science Park, Haidian District, Beijing 100084, China

Tel:    +86 10 62795180

Fax:    +86 10 62795182 

E-mail:  biotech@ittc.com.cn 

Website: www.coway.com.cn    www.coway-biotech.com