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Prednisolone

1. Product: Prednisolone (Prednisolonum) (pregnadiene-1,4-triol-11b, 17a, 21-dione-3,20, or D-1-dehydroxycortisone)

2. Strain: Non-pathogenic bacterial strain. 

3. Substrate: Hydrocortisone (Cortisol)

4. Biotechnology parameters:

1. Substrate loading (kg per kg of product): less 1.2 

2. Substrate concentration (g/l): >20 (up to 70) 

3. Duration of microbial transformation stage: 5-8 hrs 

4. Substrate conversion: 97-100 % 

5. Yield of crystalline final product - >80% 

6. Purity of product - corresponds to BP and USP requests 

5. Biotechnology advantages:

• Ecologically friendly 

• High productivity 

• High conversion degree (no residual substrate in a product) 

• Low labour- and energy consumes 

6. Contact

Add:    Room 701B/D, Building B, Science Park Tower, Tsinghua Science Park, Haidian District, Beijing 100084, China

Tel:    +86 10 62795180

Fax:    +86 10 62795182 

E-mail:  biotech@ittc.com.cn 

Website: www.coway.com.cn    www.coway-biotech.com 

 

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