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Biotransformation Method to Produce 4-AD

1. Product Presentation

Product name: 4-androstenedione (4-AD)

Chemical name: 4-Androstene-3, 17-dione

Structural formula: 

Molecular formula: C19H26O2

Molecular weight: 286.41

2. Technology property

Graph 1-1   One step biocatalysis method to produce 4-AD by phytosterol

3. Technology Property:

1) Use high conversion mutant strain of Mycobacterium, so the content of byproduct in fermentation broth will be lower.

2) If the adding amount of phytosterol as substrate is more than 25g/L, fermentation time would be 4 days with final titre of more than 10g/L; if the adding amount of phytosterol as substrate is more than 50g/L, fermentation time would be 7 days with final titre of more than 20g/L.

3) There is no need to add vegetable oil or emulgator simplifying the purification process.

4. Contact:

Add:    Room 701B/D, Building B, Science Park Tower, Tsinghua Science Park, Haidian District, Beijing 100084, China

Tel:    +86 10 62795180

Fax:    +86 10 62795182 

E-mail:  biotech@ittc.com.cn 

Website: www.coway.com.cn    www.coway-biotech.com

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